Human Genetics: This course will provide students with an overview of the fundamental principles of medical genetics. Topics will include gene structure and function, inheritance patterns, molecular genetics, population genetics, genetic epidemiology, prenatal diagnosis, developmental genetics and birth defects, cancer, pharmacogenomics, treatment, and ethical and public policy issues.

Offered by: Human Genetics

• Terms
  • Fall 2024
  • Winter 2025
• Instructors
  • Jennifer Fitzpatrick
  • Jennifer Fitzpatrick, Laurence P Baret

Human Genetics: This course will deal with ethical issues in the gathering, dissemination, and use of genetic information for decisions concerning reproduction, health care, and research.

Offered by: Human Genetics

• Terms
  • Fall 2024
  • Winter 2025
• Instructors
  • Yann Joly, Nicole Palmour, Seang Lin Tan, Palmira Granados Moreno, Ma'n Hilmi M Zawati, Anjie Ni, Diya Uberoi
  • Yann Joly, Nicole Palmour, Seang Lin Tan, Palmira Granados Moreno, Ma'n Hilmi M Zawati, Anjie Ni, Diya Uberoi

Human Genetics: Principles and concepts of the genetics of human populations.

Offered by: Human Genetics

• Terms
  • Winter 2025
• Instructors
  • Simon Gravel

Human Genetics: A review of recent advances in human genomics and current state of the art technologies of DNA sequence and whole genomics analyses, as well as future directions in the post-genomic era.

Offered by: Human Genetics

• Prerequisite: BIOL 370 or by permission of the instructor.

• Terms
  • Winter 2025
• Instructors
  • Jacek A Majewski

Human Genetics: This course will deal with recent progress in human genetics, and its applications to health care, by identifying different fields including different disciplines (e.g. cancer genetics, neurogenetics), different conceptual approaches, or different methodologic approaches.

Offered by: Human Genetics

• Terms
  • Winter 2025
• Instructors
  • Sirui Zhou, Claude Bhérer, Daniel Taliun

Human Genetics: Advanced concepts in epigenetics and chromatin regulation, experimental methods used in epigenetics research, and computational methods for analysis of epigenomics data.

Offered by: Human Genetics

• Restrictions: Not open to students who have taken or are taking PHAR 565.
• Enrolment limitations: minimum 4 students, maximum 15 students.
• Language of instruction: English
• Course is graded.

• Terms
  • Winter 2025
• Instructors
  • Hamed S Najafabadi, Vahab Soleimani

Human Genetics: Research Internship on the ethico-legal and policy issues in human genetics in both the research and the clinical settings.

Offered by: Human Genetics

• Fall or Winter

• Terms
  • Winter 2025
• Instructors
  • Ma'n Hilmi M Zawati

Human Genetics: Introduction to the field of stem cell research. Definition of stem cells. Pluripotent stem cells and reprogramming. Adult stem cells, niche and asymmetric division. Clinical applications of stem cells. Cancer stem cells. Ethical issues surrounding stem cell research and clinical treatment.

Offered by: Human Genetics

• Prerequisites: HGEN692 or equivalent Minimum grade attained by student must be: B+

• Terms
  • This course is not scheduled for the 2024 academic year
• Instructors
  • There are no professors associated with this course for the 2024 academic year

Human Genetics: This course will introduce key statistical concepts that motivate and underlie the many statistical analysis methods currently used in analysis of genetic and genomic data. Emphasis will be placed on understanding how these concepts can influence study designs and analysis choices, and when substantial unanticipated biases can occur. Concepts include an understanding of variability and error, bias and its sources, independence, how distributions of variables impact analysis, outliers, covariates, missing data, the goals of data cleaning, multiple testing, and some consideration of clustering and prediction models.

Offered by: Human Genetics

• Prerequisite(s): A course introducing basic statistics or equivalent knowledge. Registration is by permission of the course coordinator.

• Terms
  • Fall 2024
• Instructors
  • Celia M Greenwood, Robert Nadon, Claudia Kleinman, Despoina Manousaki

Human Genetics: Focus on advanced methods in genetics and their applications to understand the genetics of the brain in health and disease. Topics include high throughput sequencing, genome-wide association studies, disease models, organoids, RNA sequencing, single-cell sequencing and more to better understand the brain.

Offered by: Human Genetics

• Restriction: Open to all graduate students enrolled in Human Genetics and students in other graduate programs, with permission from the course coordinator.

• Terms
  • This course is not scheduled for the 2024 academic year
• Instructors
  • There are no professors associated with this course for the 2024 academic year

Human Genetics: The past, present, and future of cancer research and treatment with an emphasis on precision medicine driven by significant advances in genomics. Precision medicine uses genomics, RNA and protein abundance, as well as key metabolic and physiological markers to best design and implement treatment.

Offered by: Human Genetics

• Prerequisite: Approval of the course instructor.

• Terms
  • Fall 2024
• Instructors
  • Logan Walsh, Jonathan Spicer, Pierre-Olivier Fiset, Daniela Quail

Human Genetics: This course will emphasize the principles and practice of human genetics, including an overview of the fundamental aspects of human genetics pertaining to chromosomes and mutations, population, cancer and development genetics, the inheritance of complex traits.

Offered by: Human Genetics

• Restriction: For Department of Human Genetics graduate students.

• Terms
  • Fall 2024
• Instructors
  • Ken Dewar, Jamie Engert, Claude Bhérer, Yann Joly, Loydie Majewska, Yojiro Yamanaka, David Langlais, Logan Walsh, Sali Farhan, Raquel Cuella Martin

Human Genetics: Study of internet resources relevant to biomedical research.

Offered by: Human Genetics

• Restriction: As the emphasis of the course instruction will be on the human genome, a preference will be given to graduate students in the Dept. of Human Genetics. Graduate students with basic knowledge of human genome from the Faculty of Medicine can apply with permission of the course coordinator.

• Terms
  • This course is not scheduled for the 2024 academic year
• Instructors
  • There are no professors associated with this course for the 2024 academic year

Human Genetics: A review and discussion of specific topics in genetics (genetic models: population-based, animal, and in vitro genetic models, genomics, and medical genetics) centred on current literature and latest advances in the field.

Offered by: Human Genetics

• Note: Course enrolment is limited to 12 students.

• Terms
  • Winter 2025
• Instructors
  • Yasser Riaz Alhosseini, Michael Witcher, William Foulkes, Ma'n Hilmi M Zawati, Swneke D Bailey, Hamed S Najafabadi, David Labbé, Claudia Kleinman, David Langlais, Ioannis Ragoussis

Human Genetics: A review and discussion of specific topics in genetics (genetic models: population-based, animal, and in vitro genetic models, genomics, and medical genetics) centred on current literature and latest advances in the field.

Offered by: Human Genetics

• Note: Course enrolment is limited to 12 students.

• Terms
  • Winter 2025
• Instructors
  • Loydie Majewska

Experimental Medicine: Precise description of available methods in molecular genetics, and rationales for choosing particular techniques to answer questions posed in research proposals for targeting genes in the mammalian genome. Emphasis placed on analysis of regulation of gene expression and mapping, strategies for gene cloning. Course divided between lectures and student seminars.

Offered by: Medicine

• Offered in conjunction with the Department of Experimental Medicine.
• Prerequisite (Graduate): Admission by permission of instructor.

• Terms
  • Winter 2025
• Instructors
  • Danuta Radzioch

Biology (Sci): Selected human diseases, from the molecular and cellular levels to tissue effects and emerging novel therapies.

Offered by: Biology

• Fall
• Three hours lecture
• Prerequisites: BIOL 202 or BIOL 302, and BIOL300; or permission of the instructor

• Terms
  • Fall 2024
• Instructors
  • Nancy E Braverman, Jacques Jean G Genest, Miltiadis Paliouras, Karen Elizabeth Christensen, Frank Rauch, David Watkins, Eric Alan Shoubridge, Alexei Pshezhetsky, Thomas Kitzler, Gary A Armstrong

Biology (Sci): Cellular and molecular approaches to characterization of the human genome.

Offered by: Biology

• Winter
• 3 hours lecture
• Prerequisites BIOL 202 or BIOL 302; BIOL 300; BIOL 370; or permission.

• Terms
  • Winter 2025
• Instructors
  • Jamie Engert, Rima Slim, Alexandre Montpetit, Bruce Gottlieb, Ma'n Hilmi M Zawati, Hamed S Najafabadi, Yojiro Yamanaka, David Langlais, Javad Nadaf, Jean-Baptiste Riviere